PDO provides a data-access abstraction layer, which means that, regardless of which database you're using, you use the same functions to issue queries and fetch data. PDO does not provide a database abstraction; it doesn't rewrite SQL or emulate missing features. You should use a full-blown abstraction layer if you need that facility.

PDO ships with PHP 5.1, and is available as a PECL extension for PHP 5.0; PDO requires the new OO features in the core of PHP 5, and so will not run with earlier versions of PHP.